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DOSAGE AND ADMINISTRATION OXYCONTIN need to be prescribed only by healthcare industry experts that are experienced about the use of prolonged-release/extensive-acting opioids and how to mitigate the connected hazards. (2.1)

To cut back the potential risk of dizziness and lightheadedness, get up gradually when rising from the sitting down or lying situation.

Does oxycodone oral communicate with other medications you might be taking? Enter your medication into the WebMD conversation checker

Storage Shop at place temperature faraway from mild and dampness. Don't store in the bathroom. Hold all remedies from kids and Animals. See also Warning portion.

Each time a patient no more calls for therapy with oxycodone, it might be sensible to taper the dose little by little to circumvent signs of withdrawal. In absence of enough ache Management, the possibility of hyperalgesia, tolerance and development of fundamental illness really should be regarded as (see section 4.4).

Drug interactions may well transform how your prescription drugs function or increase your threat for really serious Unwanted effects. This document does not have all probable drug interactions.

Though it can help Lots of individuals, this medication may perhaps at times trigger addiction. This hazard could possibly be larger In case you have a material use problem (including overuse of or dependancy to medicines/alcohol).

Abruptly halting this medication may perhaps trigger withdrawal, particularly if you may have utilised it for years or in significant doses. To stop withdrawal, your medical doctor may perhaps lower your dose little by little.

Just before using oxycodone, tell your physician or pharmacist For anyone who is allergic to it; or to other opioid suffering relievers (like oxymorphone); or if you have some other allergies.

Oxycodone may possibly improve the neuromuscular blocking action of skeletal muscle relaxants and deliver an increased degree of respiratory depression.

When severe, everyday living-threatening, or fatal respiratory despair can take place at any time during the use of OXYCONTIN, the chance is greatest through the initiation of therapy or adhering to a dosage boost.

Concomitant usage of OXYCONTIN with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could reduce oxycodone plasma concentrations, minimize opioid efficacy or, potentially, cause a withdrawal syndrome website inside of a affected individual who had produced Bodily dependence to oxycodone.

Acute or extreme bronchial bronchial asthma in an unmonitored setting or in absence of resuscitative tools (four)

When employing OXYCONTIN with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, Assess individuals at frequent intervals and take into account increasing the opioid dosage if necessary to take care of satisfactory analgesia or if signs of opioid withdrawal take place [see Drug Interactions (seven)].